非连续采空区矿柱力学分析的数值模拟

为探讨非连续采空区矿柱力学原理，通过FLAC3D数值模拟技术，对下向水平分层进路式胶结充填采矿法开采形成的非连续采空区中矿柱的受力状态进行了分析。研究表明，非连续采空区中矿柱所受的力主要为覆岩的自重应力，水平应力对其影响不大；随着埋深的增加矿柱承受的垂直方向的力近似呈直线增加；随着非连续采空区跨度的增加（进路数量增加），非连续采空区受垂直方向的应力逐渐由围岩两侧向矿柱中间过渡。     

复杂应力区段煤柱合理留设宽度仿真研究

针对南关煤矿3205运输巷道工作面掘进与支护困难、巷道变形严重且维修频繁的现状,为破解复杂应力情况下煤柱合理留设宽度这一关键性问题,借助FLAC 3D软件进行了应力场与位移场仿真分析。研究结果表明:显著的水平应力场、邻近的采动应力场与劣化的围岩稳定性三重因素的综合作用是制约3205运输巷正常掘进作业的瓶颈。在不同煤柱宽度方案比选过程中,窄煤柱在应对较强水平应力与剪切应力作用时处于劣势。煤柱宽度越大,采动应力场对煤柱及工作面的影响越小,采掘活动更为安全。经过方案比选,最终确立留设煤柱在复杂应力区段的合理宽度为30 m。     

模拟水环境下的压紧弹簧刚度试验及计算模型的研究

在模拟水环境下，对堆内构件压紧弹簧的缩比试样进行了刚度试验，并与有限元模拟、基于小扰度理论模型和大扰度随动模型的分析结果进行比较分析。结果表明，当摩擦系数按文献实验测值0.189取值时，有限元模拟、基于小扰度的理论模型和大扰度随动模型计算所得的刚度值均与试验所得的相近；卸载稳定段的刚度均明显小于加载稳定段的，是加载时的0.6倍左右。有限元模拟分析进一步阐明，在压紧弹簧变形过程中，压紧弹簧的截面存在转动，它与垫板之间的接触点并不是固定的，在加载和卸载过程中存在来回的径向位移。并且压紧弹簧接触面上的摩擦力方向是相反的，使得压紧弹簧在加载和卸载过程的刚度存在较大的差别。较小扰度理论模型、考虑压紧弹簧截面转动和接触点径向位移的大扰度随动模型所得的结果与有限元模拟更为接近。      

钠水反应试验系统中小泄漏钠水反应氢气分布特性

蒸汽发生器是钠冷快堆的关键设备之一，其传热管破裂引发的钠水反应会产生大量氢气及热量，危害钠冷快堆的安全运行。本文基于VOF多相流模型，在钠水反应试验系统内开展中小泄漏钠水反应工况的数值分析，获得了高压反应釜内氢气在钠水反应下的三维空间分布特性和迁移特性。结果表明：高压反应釜内氢气的迁移特性受钠液流速影响，氢气在整个循环环路的迁移特性主要受水泄漏量控制。通过设置灵敏度为0.005 ppm的氢计，获得了环路不同区域检测到氢气的最快特征时间。     

Tissue-Specific Ferritin- and GFP-Based Genetic Vectors Visualize Neurons by MRI in the Intact and Post-Ischemic Rat Brain

(1) Background: Neurogenesis is considered to be a potential brain repair mechanism and is enhanced in stroke. It is difficult to reconstruct the neurogenesis process only from the histological sections taken from different animals at different stages of brain damage and restoration. Study of neurogenesis would greatly benefit from development of tissue-specific visualization probes. (2) Purpose: The study aimed to explore if overexpression of ferritin, a nontoxic iron-binding protein, under a doublecortin promoter can be used for non-invasive visualization of neurogenesis using magnetic resonance imaging (MRI). (3) Methods: Ferritin heavy chain (FerrH) was expressed in the adeno-associated viral backbone (AAV) under the doublecortin promoter (pDCX), specific for young neurons, in the viral construct AAV-pDCX-FerrH. Expression of the enhanced green fluorescent protein (eGFP) was used as an expression control (AAV-pDCX-eGFP). The viral vectors or phosphate-buffered saline (PBS) were injected intracerebrally into 18 adult male Sprague–Dawley rats. Three days before injection, rats underwent transient middle-cerebral-artery occlusion or sham operation. Animals were subjected to In vivo MRI study before surgery and on days 7, 14, 21, and 28 days after injection using a Bruker BioSpec 11.7 T scanner. Brain sections obtained on day 28 after injection were immunostained for ferritin, young (DCX) and mature (NeuN) neurons, and activated microglia/macrophages (CD68). Additionally, RT-PCR was performed to confirm ferritin expression. (4) Results: T2* images in post-ischemic brains of animals injected with AAV-pDCX-FerrH showed two distinct zones of MRI signal hypointensity in the ipsilesioned hemisphere starting from 14 days after viral injection—in the ischemic lesion and near the lateral ventricle and subventricular zone (SVZ). In sham-operated animals, only one zone of hypointensity near the lateral ventricle and SVZ was revealed. Immunochemistry showed that ferritin-expressing cells in ischemic lesions were macrophages (88.1%), while ferritin-expressing cells near the lateral ventricle in animals both after ischemia and sham operation were mostly mature (55.7% and 61.8%, respectively) and young (30.6% and 7.1%, respectively) neurons. RT-PCR confirmed upregulated expression of ferritin in the caudoputamen and corpus callosum. Surprisingly, in animals injected with AAV-pDCX-eGFP we similarly observed two zones of hypointensity on T2* images. Cellular studies also showed the presence of mature (81.5%) and young neurons (6.1%) near the lateral ventricle in both postischemic and sham-operated animals, while macrophages in ischemic lesions were ferritin-positive (98.2%). (5) Conclusion: Ferritin overexpression induced by injection of AAV-pDCX-FerrH was detected by MRI using T2*-weighted images, which was confirmed by immunochemistry showing ferritin in young and mature neurons. Expression of eGFP also caused a comparable reduced MR signal intensity in T2*-weighted images. Additional studies are needed to investigate the potential and tissue-specific features of the use of eGFP and ferritin expression in MRI studies.     

潮流能水平轴水轮机在剪切来流下的水动力分析

采用基于计算流体力学方法的全尺度数值模拟计算,建立了适用于潮流能水轮机模拟的剪切来流环境,通过数值计算结果,对潮流能水轮机随时间变化的宏观力和流场特征进行了系统分析,探索水轮机在复杂工况下的水动力特性规律。结果表明,水轮机整个叶轮的总体平均受力在剪切流工况中未受到明显影响; 单个叶片的瞬态轴向力系数和瞬态轴向扭矩系数在旋转周期内出现了明显的周期性变化,且周期性变化幅值随转速增大而增大; 非定常的瞬时轴向扭矩和力的周期性振荡容易引起单个叶片的结构性振动,可能对水轮机的机械结构造成影响。     

An improved damage diagnostic technique based on Singular Spectrum Analysis and time series models

An approach to enhance the sensitivity of the damage index using the prediction errors of autoregressive – autoregressive exogenous models by augmenting Singular Spectrum Analysis (SSA) to detect and locate minor damage is presented. Numerical simulation studies are carried out by considering a simply supported beam with single and multiple cracks. An experimental study on a reinforced cement concrete beam has been carried out to validate the technique using different levels of damage. The studies emphasise that the SSA improves the sensitivity of the damage index for detection and also localisation, handling environmental/operational variability and measurement noise.     

Quantitative assessments of performance and robustness of maintenance policies for stochastically deteriorating production systems

Over the last few decades, many efforts have been invested in improving the economic performances of maintenance policies for stochastically deteriorating production systems. However, with the development of complex production systems, maintenance managers are interested not only in cost saving, but also in how to trustworthily plan and allocate the required maintenance budget. In this context, the robustness of maintenance policies which is related to the maintenance cost variability from a renewal cycle to another plays a pivotal role. This research deals with a quantitative approach to jointly assess the economic performance and robustness of some representatives of two most well-known classes of maintenance policies: time-based and condition-based maintenance. To this end, we first propose a new cost criterion which combines the long-run expected cost rate and standard deviation of maintenance cost per renewal cycle. Then, we develop and compare the associated mathematical cost models of the considered maintenance policies on the basis of the Gamma degradation process and the theory of stochastic renewal processes. The comparison results under different situations of maintenance costs and system characteristics show that the optimal configuration of maintenance policies gives the best compromise between the performance and robustness, and is mostly affected by the system downtime. Under this aspect, the condition-based maintenance remains more profitable than the time-based maintenance. Still, maintenance managers could implement condition-based maintenance policies that efficiently control the downtime to maximise the maintenance effectiveness of production systems from both performance and robustness viewpoints.     

Neural network-based hybrid models developed for free radical polymerization of styrene

In the present work, the free radical polymerization of styrene is modeled by considering the phenomenology of the process (a simplified model, which does not include the diffusional effects, gel, and glass effects) in combination with an empirical model represented by an artificial neural network. Differential evolution (DE) algorithm, belonging to the class of evolutionary algorithms, is applied for developing the neural models in optimal forms. For improving the results—predicted conversion and molecular weights as function of time, temperature, and initiator concentration—different combinations between phenomenological model and neural network are tested; also, individual and stacked neural networks have been developed for the polymerization process. This methodology based on hybrid models, including neural networks aggregated in stacks, provides accurate results.     

带扩张段构型超声速气流中横向射流数值模拟

针对带扩张段构型的发动机燃烧室,采用欧拉-拉格朗日仿真方法研究喷注方式、喷孔参数及隔离段燃烧室构型的改变对于射流雾化效果的影响,用以更好地指导发动机设计.结果表明,在保证发动机总体流量不变的条件下,喷孔孔径减小或者喷孔总数量减少使得液气动量通量比增大,有利于同时增大单孔射流穿透深度以及液滴展向宽度.贫燃工况下如当量比为0.7条件下,射流流量减小,混合效果可能变差.而在发动机结构设计方面,隔离段到燃烧室的过渡设计不宜采用大转角,15°转角是相对较为理想的设计方案.采用小角度突扩构型设计比渐扩构型更容易找到相对好的点火位置.